Detection limit: 2 pg/ml
Detection range: 0 to 250 pg/ml

Free Osteoprotegerin (human) Detection Set [For ELISA Application]
Prod. No. APO-54N-028

For the quantitative determination of human free osteoprotegerin (not bound to RANKL or TRAIL) in cell culture supernatant, plasma and serum.

Figure: Netrin-1 (human) (recombinant) (Prod. No. ALX-522-100) mediates commissural axon outgrowth of dorsal spinal cord cells from rat embryos.

Also available:

Netrin-1 (mouse) (recombinant)   Prod. No. ALX-522-124
Netrin-1 (chicken) (recombinant) Prod. No. ALX-522-106

• First commercial source for IL-33 from rat!
• All IL-33 proteins from human and mouse are positively tested to activate the ST2-dependent NF-κB pathway!
• ≥90 % pure (SDS-PAGE)
• Endotoxin-free

IL-33 (human) (recombinant)             Prod. No. ALX-522-098
IL-33 (human) (recombinant)             Prod. No. ALX-201-363
IL-33 (human) (recombinant) (His)   Prod. No. ALX-201-350
IL-33 (mouse) (recombinant)             Prod. No. ALX-522-101
IL-33 (mouse) (recombinant) (His)   Prod. No. ALX-201-361
IL-33 (rat) (recombinant)                    Prod. No. ALX-522-125

PI-103  Prod. No. ALX-270-460

Purity ≥ 97 % (HPLC)

Nesfatin-1 is an important satiety molecule associated with melanocortin signaling in the hypothalamus.

MAb to Nesfatin-1 (Nesfaty-1)  Prod. No. ALX-804-854

• Recognizes mouse and rat nesfatin-1 and its precursor nucleobindin-2
• Immunogen: Recombinant rat nesfatin-1 (aa 25-106) (Prod. No. ALX-522-118)
• Clone: Nesfaty-1
• Application: Western blot
• Purity: ≥95% (SDS-PAGE), Protein G-affinity purified

Figure 1: Beclin1 and Ambra-1 (activating molecule in Beclin 1-regulated autophagy) co-localize in mammalian cells.

Ambra-1 is a positive regulator of Beclin1-dependent autophagy and has a crucial role in embryonic nervous system development.

PAb to Ambra-1 Prod. No. CVL-PAB0224

• Recognizes human, mouse and rat Ambra-1
• Immunogen: Synthetic peptide corresponding to the N-terminus of mouse Ambra-1
• Applications: IHC, IP, Western blot

Vaspin (human) ELISA Kit (Prod. No. AG-V0712)

For the quantitative determination of vaspin in human serum, plasma or cell culture supernatants. Manufactured by AdipoGen, Inc., the specialists in diabetes and obesity research.

MAb to Visfatin (OMNI379)  Prod. No. ALX-804-717

• Recognizes human, mouse and rat Visfatin
• Applications: ELISA, IHC (PS), WB

Echinomycin  Prod. No. ALX-380-201

• Isolated from Streptomyces sp. MST-AS5446
• Purity ≥ 99% as determined by HPLC
  

BIX 01294             Prod. No. ALX-270-473
HSD Inhibitor 23  Prod. No. ALX-270-474
4EGI-1                    Prod. No. ALX-430-155

• High Purity (≥ 95 %)
• High level quality controlled by 1H-NMR, 13C-NMR and MS

Figure: Immunohistochemistry using 2 µg/ml of MAb to RUNX3 (human) (R3-6E9) (Prod. No. ALX-803-318) applied to normal human gastric paraffin sections [1].

Also available:

MAb to RUNX3 (human) (R3-5G4)  Prod. No. ALX-803-319
MAb to RUNX3 (R3-1E10)                 Prod. No. ALX-803-320

For the quantitative determination of HNE-histidine conjugates in human cell lysates either induced by mild oxidative stress:

HNE-histidine FINE ELISA Kit  Prod. No. ALX-850-320

or induced by strong oxidative stress:

HNE-histidine STRESS ELISA Kit  Prod. No. ALX-850-322

AS-252424  Prod. No. ALX-270-465

Potent and selective phosphoinositide 3-kinase (PI(3)K) p110γ inhibitor shown to be selective for class IB PI(3)K-mediated cellular effects [1,4].

AS-604850  Prod. No. ALX-270-461
AS-605240  Prod. No. ALX-270-462

Potent, cell permeable and ATP-competitive inhibitors of phosphoinositide 3-kinase (PI(3)K) p110γ with proven selectivity over other PI(3)K isoforms [2,3,5].

TGX-221  Prod. No. ALX-270-464

Purity ≥98% as determined by NMR

Compound 15e  Prod. No. ALX-270-455

Purity ≥99% as determined by HPLC!

(+)-Madindoline A  Prod. No. ALX-350-328

A potent IL-6 inhibitor manufactured by the Kitasato Institute, Tokyo.