Ac-DMQD-CHO |
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| SYNONYMS | Caspase-3 Inhibitor (Aldehyde) |
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| PRODUCT LINE | Cell Death / Apoptosis / Autophagy |
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| PRODUCT FAMILIES | Caspase Inhibitors |
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| Ordering Information |
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| Product Numbers | Format | Size | Unit Price | Quantity | | | ALX-260-077-M001 |
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1 mg | | | | | ALX-260-077-M005 |
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5 mg | | | | | | |
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| Product Specification |
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| SEQUENCE: | Ac-Asp-Met-Gln-Asp-CHO |
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| FORMULA: | C20H31N5O10S |
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| MW: | 533.6 |
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| PEPTIDE CONTENT: | 70-90%. |
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| PURITY: | ≥96% (HPLC) |
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| APPEARANCE: | White powder. |
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| FORMULATION: | Lyophilized. |
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| SOLUBILITY: | Soluble in distilled water. |
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| SHIPPING: | AMBIENT |
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| LONG TERM STORAGE: | -20°C |
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| USE/STABILITY: | Stock solutions should be divided into aliquots and stored at -20°C. |
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| HANDLING: | Keep cool and dry. |
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| Product Description |
Reversible inhibitor of caspase-3. Together with the caspase-6 inhibitor Ac-VEID-CHO (Prod. No. ALX-260-062) this inhibitor has been used to dissect the pathway of caspase activation in Fas-stimulated Jurkat cells. |
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| | Product Specific Literature References | | Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis: H. Hirata, et al.; J. Exp. Med. 187, 587 (1998) Abstract |
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| RELATED PRODUCT GROUPS |
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