Ac-DMQD-AMC |
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| SYNONYMS | Caspase-3 Substrate (Fluorogenic) |
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| PRODUCT LINE | Cell Death / Apoptosis / Autophagy |
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| PRODUCT FAMILIES | Caspase Substrates |
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| Ordering Information |
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| Product Numbers | Format | Size | Unit Price | Quantity | | | ALX-260-078-M001 |
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1 mg | | | | | ALX-260-078-M005 |
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5 mg | | | | | | |
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| Product Specification |
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| SEQUENCE: | Ac-Asp-Met-Gln-Asp-AMC (AMC=7-Amino-4-methylcoumarin) |
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| FORMULA: | C30H38N6O12S |
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| MW: | 706.7 |
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| PEPTIDE CONTENT: | 75-95%. |
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| PURITY: | ≥98% (HPLC) |
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| APPEARANCE: | White powder. |
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| SOLUBILITY: | Soluble in DMSO. Dilute with distilled water or buffer. Also soluble in phosphate buffer, pH 7.5 |
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| SHIPPING: | AMBIENT |
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| LONG TERM STORAGE: | -20°C |
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| HANDLING: | Keep cool and dry. |
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| Product Description |
Fluorogenic substrate for caspase-3. |
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| | Product Specific Literature References | Bid truncation, bid/bax targeting to the mitochondria, and caspase activation associated with neutrophil apoptosis are inhibited by granulocyte colony-stimulating factor: N.A. Maianski, et al.; J. Immunol. 172, 7024 (2004) Abstract
The effects of TNF-alpha and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status: M. Kovarikova, et al.; Differentiation 72, 23 (2004) Abstract
Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells: J. Hofmanova; Eur. J. Nutrition 44, 40 (2005) Abstract |
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| | General Information | |
Background/Technical Information | | AMC has an excitation maximum of 380nm and an emission maximum of 460nm. | | |
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| RELATED PRODUCT GROUPS |
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