Signal Transduction



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 ALX-260-084[ALEXIS] Revised 24-Feb-05  

Ac-LEVD-AFC

SYNONYMS   

Caspase-4 Substrate (Fluorogenic)

PRODUCT LINE   

Cell Death / Apoptosis / Autophagy

PRODUCT FAMILIES   

Caspase Substrates

Ordering Information
 Product NumbersFormatSizeUnit PriceQuantity
 ALX-260-084-M001 1 mg  
 ALX-260-084-M005 5 mg  
Product Specification
SEQUENCE:   Ac-Leu-Glu-Val-Asp-AFC (AFC=7-Amido-4-trifluoromethylcoumarin)
 
FORMULA:   C32H40F3N5O11
 
MW:   727.7
 
PEPTIDE CONTENT:   75-95%.
 
PURITY:   ≥99% (HPLC)
 
APPEARANCE:   White to off-white powder.
 
SOLUBILITY:   Soluble in DMSO. Dilute with distilled water or buffer. Also soluble in phosphate buffer, pH 7.5-8.0.
 
SHIPPING:   AMBIENT
 
LONG TERM STORAGE:   -20°C
 
USE/STABILITY:   Dissolve only as much as needed at one time because of the possibility of decomposition in solution. Store solution at -20°C. Protect from condensation: when taking the sample out of the container, wait until it warms up to room temperature, then open it.
 
HANDLING:   Keep cool and dry.
Product Description

Fluorogenic substrate for caspase-4. Similar to the fluorogenic substrate Ac-LEVD-AMC (Prod. No. ALX-260-083); the AFC fluorophore is more sensitive.

General Information

Background/Technical Information   
AFC has an excitation maximum of 400nm and an emission maximum of 505nm.
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