Signal Transduction



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 ALX-260-114[ALEXIS] Revised 24-Feb-05  

Ac-AEVD-AFC

SYNONYMS   

Caspase-6 Substrate (Fluorogenic)
Caspase-8 Substrate (Fluorogenic)

PRODUCT LINE   

Cell Death / Apoptosis / Autophagy

PRODUCT FAMILIES   

Caspase Substrates

Ordering Information
 Product NumbersFormatSizeUnit PriceQuantity
 ALX-260-114-M005 5 mg  
 ALX-260-114-M010 10 mg  
Product Specification
SEQUENCE:   Ac-Ala-Glu-Val-Asp-AFC (AFC=7-Amino-4-trifluoromethylcoumarin)
 
FORMULA:   C29H34F3N5O11
 
MW:   685.6
 
PURITY:   ≥97% (HPLC)
 
APPEARANCE:   White to off-white powder.
 
SOLUBILITY:   Soluble in DMSO.
 
SHIPPING:   AMBIENT
 
LONG TERM STORAGE:   -20°C
 
HANDLING:   Keep cool and dry.
Product Description

Fluorogenic substrate for caspase-6 and -8.

General Information

Background/Technical Information   
AFC has an excitation maximum of 400nm and an emission maximum of 505nm.
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