Signal Transduction



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 ALX-270-039[ALEXIS] Revised 15-Nov-06  

A-3 . hydrochloride

SYNONYMS   

N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide . HCl

PRODUCT LINE   

Signal Transduction

PRODUCT FAMILIES   

PKA Inhibitors

Ordering Information
 Product NumbersFormatSizeUnit PriceQuantity
 ALX-270-039-M010 10 mg  
 ALX-270-039-M050 50 mg  
Product Specification
FORMULA:   C12H13ClN2O2S . HCl
 
MW:   284.8 . 36.5
 
PURITY:   ≥98%
 
APPEARANCE:   White to off-white solid.
 
SOLUBILITY:   Soluble in DMSO or 100% ethanol.
 
SHIPPING:   AMBIENT
 
LONG TERM STORAGE:   -20°C

Product Description

Inhibitor of cAMP- and cGMP-dependent protein kinase (PKA and PKG), protein kinase C (PKC), casein kinase I and II, and myosin light chain kinase.

Product Specific Literature References
Naphthalenesulfonamides as calmodulin antagonists and protein kinase inhibitors: M. Inagaki, et al.; Mol. Pharmacol. 29, 577 (1986) Abstract
RELATED PRODUCT GROUPS   

Signal Transduction > Protein Kinase C [PKC] / Related Products > PKC Inhibitors / Signal Transduction > Wnt Signalling Pathway / Related Products > Casein Kinase / Related Products > Casein Kinase Inhibitors / Signal Transduction > Kinases / Related Products > Serine / Threonine Kinases / Related Products > Myosin Light Chain Kinases / Related Products > Myosin Light Chain Kinase Inhibitors / Signal Transduction > cGMP Pathways > cGMP-dependent Protein Kinase [PKG] / Related Products > PKG Inhibitors