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 ALX-340-063[ALEXIS] Revised 19-Apr-07  

N-Arachidonoyl-L-serine

SYNONYMS   

N-[(5Z,8Z,11Z,14Z)-1-Oxo-5,8,11,14-eicosatetraenyl)]-L-serine
ARA-S

PRODUCT LINE   

Neurobiology

PRODUCT FAMILIES   

Endocannabinoids

Ordering Information
 Product NumbersFormatSizeUnit PriceQuantity
 ALX-340-063-M010 10 mg  
Product Specification
FORMULA:   C23H37NO4
 
MW:   391.5
 
CAS NUMBER:   187224-29-9
 
PURITY:   ≥98%
 
APPEARANCE:   Waxy solid.
 
SOLUBILITY:   Soluble in DMSO or dimethyl formamide; sparingly soluble in water.
 
SHIPPING:   SHIPPED ON DRY ICE
 
LONG TERM STORAGE:   -80°C

Product Description

Endocannabinoid-like brain constituent with similar biological profile like abnormal cannabidiol. Binds weakly to CB1 and CB2 receptors and TRPV1. Produces endothelium-dependent vasodilation. Increases phosphorylation of Akt and mitogen-activated protein kinase (MAPK) in HUVEC.

Product Specific Literature References
N-arachidonoyl L-serine, an endocannabinoid-like brain constituent with vasodilatory properties: G. Milman, et al.; PNAS 103, 2428 (2006) Full Text; http://www.pnas.org/cgi/reprint/103/7/2428
RELATED PRODUCT GROUPS   

Signal Transduction > PI(3)K-Akt-mTOR Pathway > PI(3)K-Akt-mTOR Pathway Other Products / Neurobiology > TRPVs [Vanilloid Receptors] / Related Products > Endovanilloids / Signal Transduction > MAP Kinase Pathways > MAPK Pathway Activators