Apg3p (human) (recombinant) (His) |
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| SYNONYMS | Apg3L (human) (recombinant) (His)
Autophagy Protein 3-like (human) (recombinant) (His)
ATG3 |
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| PRODUCT LINE | Cell Death / Apoptosis / Autophagy |
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| PRODUCT FAMILIES | Autophagy-related Proteins [APG; ATG] / Related Products |
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| Ordering Information |
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| Product Numbers | Format | Size | Unit Price | Quantity | | | BST-E2-670-C050 |
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50 µg | | | | | BST-E2-670-C100 |
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100 µg | | | | | | |
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| Product Specification |
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| MW: | ~36.8kDa. |
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| PURITY: | ≥95% (SDS-PAGE) |
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| SHIPPING: | SHIPPED ON DRY ICE |
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| LONG TERM STORAGE: | -80°C |
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| HANDLING: | Avoid freeze/thaw cycles. |
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| Product Description |
Apg3p is the E2-like enzyme necessary for the covalent conjugation of human Apg8 modifier proteins to lipid phosphatidylethanolamine (PE) and is essential in autophagosomal membrane formation. The Apg8 ubiquitin-like proteins (including GABARAP, GATE-16, MAP-LC3) are first activated by the E1-like activating enzyme Apg7p. Apg7p forms a complex with Apg3p which subsequently forms a glycyl thioester bond with Apg8 proteins through its active site cysteine (C264). |
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| | General Information | |
Background/Technical Information | | Please click here for the Original Manufacturer’s Data Sheet.
Our product description may differ slightly from the Original Manufacturer’s Data Sheet. | | |
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| RELATED PRODUCT GROUPS |
Proteins > Recombinant Proteins / Fusion Proteins / Ubiquitin & Proteasome > Ubiquitination > Ubiquitin-conjugating Enzymes [E2] |
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